Much research shows it is possible to design motivating and healthy work, which in turn has positive consequences for individuals and their organizations. In this presentation, I argue that these dominant motivational and job strain perspectives on work design continue to be important but are insufficient, especially in the context of current challenges. In this presentation, I advocate some specific new directions. First, in light of continued large numbers of poor quality jobs, I propose that more attention should be given to the factors that shape the design of work, that is, the antecedents of work design. Second, I propose the importance of work design as a vehicle for individual growth and development. Third, I identify important topics for work design given artificial intelligence and other technological changes occurring in work. I present illustrative studies relevant to these future directions.